Check Closely (1)pentobarbital will reduce the level or effect of glecaprevir/pibrentasvir by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
Check Closely (1)pentobarbital will reduce the extent or influence of exemestane by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. For individuals acquiring exemestane using a potent CYP3A4 inducer the suggested dose of exemestane is fifty mg each day after a meal.
Phenobarbital appears to interfere Along with the absorption of orally administered griseofulvin, So lowering its blood stage.
pentobarbital will decrease the extent or influence of fludrocortisone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
pentobarbital will lessen the extent or impact of indinavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will lower the extent or outcome of levoketoconazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unfamiliar.
pentobarbital will reduce the level or result of bortezomib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
Contraindicated (1)pentobarbital will lessen the level or result of elbasvir/grazoprevir by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lower the extent or influence of fedratinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Impact of coadministering a powerful CYP3A4 inducer with fedratinib has not been analyzed.
pentobarbital will lower the extent or effect of atogepant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Carefully. Suggested atogepant dosage with concomitant usage of strong or reasonable CYP3A4 inducers is thirty mg or 60 mg qDay.
pentobarbital will reduce the extent or outcome of lonafarnib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Lonafarnib can be a delicate CYP3A4 substrate. Coadministration with solid or reasonable CYP3A4 inducers is contraindicated.
pentobarbital will lower the level or influence of tramadol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of. Decreased AUC of tramadol as well as Lively metabolite (O-desmethyltramadol) when coadministered with powerful CYP3A4 and CYP2B6 inducers
pentobarbital will lessen check here the level or influence of buprenorphine subdermal implant by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Carefully. Check sufferers presently on buprenorphine subdermal implant who demand newly-initiated therapy with CYP3A4 inducer for signs and signs of withdrawal.
fentanyl intranasal and pentobarbital both maximize sedation. Keep away from or Use Alternate Drug. Restrict use to individuals for whom choice therapy selections are inadequate